THE CHARACTERISTICS OF HYPOGLYCEMIA IN LOW BIRTH WEIGHT NEONATES AT THAI NGUYEN NATIONAL HOSPITAL | Ly | TNU Journal of Science and Technology

THE CHARACTERISTICS OF HYPOGLYCEMIA IN LOW BIRTH WEIGHT NEONATES AT THAI NGUYEN NATIONAL HOSPITAL

About this article

Received: 09/07/24                Revised: 17/10/24                Published: 18/10/24

Authors

1. Nguyen Vu Mai Ly Email to author, TNU - University of Medicine and Pharmacy
2. Nguyen Thi Xuan Huong, TNU - University of Medicine and Pharmacy
3. Tran Thi Lan Anh, TNU - University of Medicine and Pharmacy

Abstract


Hypoglycemia is the commonest metabolic disorder of neonates, especially low birth weight neonates. The study aimed to describe the proportion, clinical characteristics of hypoglycemia in low birth weight neonates at Thai Nguyen National Hospital. This is a cross-sectional descriptive study design, including 170 children from 1 day to 28 days diagnosed with low birth weight according to World Health Organization standards, venous blood glucose test was performed immediately upon admission at Thai Nguyen National Hospital, from August, 2023 to May, 2024. The results showed that: overall incidence of hypoglycemia was 64.1%. Of which, severe hypoglycemia accounts for 22%, moderate hypoglycemia accounts for 78%. Whereas, gestational age and low birth weight, were significantly related to hypoglycemia in low birth weight neonates. Most common clinical signs were tachypnea 82.6%, cyanosis 6.4%, apnea 30.3%, hypothermia 2.8%. Espiratory failure was significantly noticed with hypoglycemia (88.1%), then neonatal jaundice (9.2%), sepsis and neonatal polycythemia (4.6%).

Keywords


Hypoglycemia; Low birth weight neonates; Premature neonates; Small gestational age; Espiratory failure

References


[1] World Health Organization, "Low birthweight prevalence," 2020. [Online]. Available: https://www.who.int/data/gho/data/indicators/indicator-details/GHO/low-birth-weight-prevalence-(-). [Accessed April. 30, 2024].

[2] M. L. D. Adnyana, I. G. N. Sanjaya, M. Sukmawati, N. P. S. Purniti, I. B. Subanada, and I. W. Gustawan, "Mortality of neonatal sepsis with abnormal blood glucose level," American Journal of Pediatrics, vol. 7, no. 1, pp. 9-13, 2021.

[3] D. L. Harris, P. J. Weston, and J. E. Harding, "Incidence of neonatal hypoglycemia in babies identified as at risk," The Journal of pediatrics, vol. 161, no. 5, pp. 787-791, 2012.

[4] T. T. Hoang and Y. T. T. Hoang, "Hypoglycemia in low birth weight newborns: incidence, clinical manifestations and rick factors," (in Vietnamese), DEMACVN - Diabetes Endocrinology, vol. 33, p. 4, 2020.

[5] H. T. Hoang, "Some risk fectors in low birth weight neonates at Thai Nguyen National Hospital," (in Vietnamese), Thesis of resident doctor, TNU - University of Medicine and Pharmacy, 2022.

[6] B. T. T. Nguyen and V. N. Vo, "Hypoglycemia im sick neonates with low birth weight," (in Vietnamese), Vietnam Medical Journal, vol. 524, no. 1B, pp. 219-222, 2023.

[7] A. Saini, B. K. Gaur, and P. Singh, "Hypoglycemia in low birth weight neonates: frequency, pattern, and likely determinants," Int J Contemp Pediatrics, vol. 5, no. 2, p. 7, 2018.

[8] J. M. Kerstjens, I. F. Bocca-Tjeertes, A. F. de Winter, S. A. Reijneveld, and A. F. Bos, "Neonatal morbidities and developmental delay in moderately preterm-born children," Pediatrics, vol. 130, no. 2, pp. e265-e272, 2012.

[9] World Health Organization, "UNICEF-WHO low birthweight estimates: levels and trends 2000-2015," 2019.

[10] T. T. D. Nguyen and T. M. Vo, "Prevalence of low birth weight and related factors of E De woman at general hospital in Daklak province," (in Vietnamese), Ho Chi Minh City Journal of medicine, vol. 20, no. 1, pp. 354-360, 2016.

[11] WHO, "Assessment, Findings and Management - Low Blood Glucose," in Managing Newborn Problems: A guide for doctors, nurses and midwives, 2003, pp. F91 - F92.

[12] A. Thompson-Branch and T. Havranek, "Neonatal hypoglycemia," Pediatrics in review, vol. 38, no. 4, pp. 147-157, 2017.

[13] D. H. Adamkin and R. A. Polin, "Imperfect advice: neonatal hypoglycemia," The Journal of Pediatrics, vol. 176, pp. 195-196, 2016.

[14] Y. P. Singh, T. R. Devi, D. Gangte, T. I. Devi, N. N. Singh, and M. A. Singh, "Hypoglycemia in newborn in Manipur," Journal of Medical Society, vol. 28, no. 2, p. 108, 2014.

[15] P. Nandakishore et al., "Profile of risk factors and outcome of hypoglycemia in newborns admitted in the neonatal unit of a tertiary care hospital, Asram, West Godavari District," Journal of Evolution of Medical and Dental Sciences, vol. 3, no. 18, pp. 5048-5057, 2014.

[16] R. Bromiker, A. Perry, Y. Kasirer, S. Einav, G. Klinger, and F. Levy-Khademi, "Early neonatal hypoglycemia: incidence of and risk factors. A cohort study using universal point of care screening," The Journal of Maternal-Fetal & Neonatal Medicine, vol. 32, no. 5, pp. 786-792, 2019.

[17] I. Khan, T. Muhammad, and M. Q. Khan, "Frequency and clinical characteristics of symptomatic hypoglycemia in neonates," Gomal Journal of Medical Sciences, vol. 8, no. 2, pp. 117-120, 2010.

[18] J. M. Hawdon, J. Beer, D. Sharp, and M. Upton, "Neonatal hypoglycaemia: learning from claims," Archives of Disease in Childhood-Fetal and Neonatal Edition, vol. 102, no. 2, pp. F110-F115, 2017.

[19] O. Stomnaroska, E. Petkovska, S. Jancevska, and D. Danilovski, "Neonatal hypoglycemia: risk factors and outcomes," Prilozi, vol. 38, no. 1, pp. 97-101, 2017.




DOI: https://doi.org/10.34238/tnu-jst.10737

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