CLINICAL EPIDEMIOLOGICAL CHARACTERISTICS AND COMPLICATIONS OF INFLUENZA IN CHILDREN  AT THAI NGUYEN NATIONAL HOSPITAL

Nguyễn Thị Thu Huyền; Nguyễn Thị Xuân Hương; Nguyễn Văn Kiên; Nguyễn Thị Phượng

doi:10.34238/tnu-jst.10742

CLINICAL EPIDEMIOLOGICAL CHARACTERISTICS AND COMPLICATIONS OF INFLUENZA IN CHILDREN AT THAI NGUYEN NATIONAL HOSPITAL

About this article

Received: 10/07/24 Revised: 17/10/24 Published: 18/10/24

Authors

1. Nguyen Thi Thu Huyen , TNU - University of Medicine and Pharmacy
2. Nguyen Thi Xuan Huong, TNU - University of Medicine and Pharmacy
3. Nguyen Van Kien, TNU - University of Medicine and Pharmacy
4. Nguyen Thi Phuong, TNU - University of Medicine and Pharmacy

Abstract

This study aims to describe the clinical epidemiological characteristics and complications of influenza in children at Thai Nguyen National Hospital. The cross-sectional study was conducted on 490 children under 16 years old with seasonal influenza treated at the Pediatric Center of Thai Nguyen National Hospital from 01^st April 2023 to 31^st March 2024. Research results show that the infection rates of Influenza A and Influenza B are similar. The highest number of infected children aged 12 months - 60 months, accounting for 59.2%. Influenza is most common in winter, the common chief complaints are fever and cough (89.8%). The main symptoms were fever (100%), sore throat (93.8%), runny nose (86.7%). Most patients had nomal white blood cell count and serum CRP. There are 22.3% of children suffering from complications of influenza, of which the highest rate is pneumonia (12.2%). Unvaccinated children are 4.62 times more likely to have complications from influenza infection than vaccinated children. Premature infants are 12.65 times more likely to have complications from influenza infection than full-term infants.

Keywords

Epidmiology; Seasonal flu; Children; Complications; Vaccination

Full Text:

PDF (Tiếng Việt)

References

[1] D. Iuliano et al., “Mortality, Seasonal Influenza-associated,” Lancet, vol. 391, no. 10127, pp. 1285-1300, 2018, doi: 10.1016/S0140-6736(17)33293-2.Estimates.

[2] World Health Organization, “Guidelines for the clinical management of severe illness from influenza virus infections,” 2022.

[3] V. Kumar, “Influenza in Children,” Indian J. Pediatr., vol. 84, no. 2, pp. 139-143, 2017, doi: 10.1007/s12098-016-2232-x.

[4] T. H. A. Vu and N. S. Nguyen, “Clinical epidemiological characteristics and complications of seasonal influenza at Haiphong Children's Hospital,” (in Vietnamese) Vietnam Medical Journal, vol. 503, pp. 207-215, 2021.

[5] Y. R. Bhat, “Influenza B infections in children: A review,” World J. Clin. Pediatr., vol. 9, no. 3, pp. 44-52, 2020, doi: 10.5409/wjcp.v9.i3.44.

[6] L. Mancinelli et al., “Clinical features of children hospitalized with influenza A and B infections during the 2012-2013 influenza season in Italy,” BMC Infect. Dis., vol. 16, no. 1, pp. 1-8, 2016, doi: 10.1186/s12879-015-1333-x.

[7] K. W. Hong, H. J. Cheong, J. Y. Song, J. Y. Noh, T. U. Yang, and W. J. Kim, “Clinical manifestations of influenza A and B in children and adults at a tertiary hospital in Korea during the 2011–2012 season,” Jpn. J. Infect. Dis., vol. 68, no. 1, pp. 20-26, 2015, doi: 10.7883/yoken.JJID.2013.466.

[8] A. Losier, G. Gupta, and M. Caldararo, “The Impact of Coronavirus Disease 2019 on Viral, Bacterial , and Fungal Respiratory Infections,” Clin Chest Med, vol. 44, no. 2, pp. 407-423, 2020.

[9] Ministry of Health, Guide to diagnosis and treatment, pp. 496-500, 2015.

[10] T. T. H. Le, “Epidemiological, clinical, para-clinical characteristics, complications and results of treatment of flu in children at Vinh Medical University Hospital,” (in Vietnamese), Vietnam Medical Journal, vol. 536, no. 2, pp. 181-185, 2024.

[11] T. D. Bui, T. H. Bui, and N. S. Nguyen, “Clinical epidemiological characteristics and complications of influenza type B at Haiphong Children's Hospital,” (in Vietnamese), Vietnam Medical Journal, vol. 536, no. 1, pp. 277-282, 2024.

[12] R. Morgan and S. L. Klein, “The intersection of sex and gender in the treatment of influenza, Current Opinion in Virology,” Curr. Opin. Virol., vol. 35, pp. 35-41, 2019, doi: 10.1016/j.coviro.2019.02.009.

[13] T. H. Nguyen et al., “Circulation and characteristics of seasonal influenza viruses in southern Vietnam in the period 2018 - 2020,” (in Vietnamese), Vietnam Journal of Preventive Medicine, vol. 32, no. 4, pp. 157-166, 2022.

[14] M. C. Nguyen et al., “Epidemiological, clinical characteristics and the association between influenza vaccination, oseltamivir treatment, and complications in children with seasonal influenza,” Minist. Sci. Technol. Vietnam, vol. 66, no. 2, pp. 82-88, 2024, doi: 10.31276/vjste.66(2).82-88.

[15] B. D. Stamm et al., “The Influence of Rapid Influenza Diagnostic Testing on Clinician Decision-Making for Patients with Acute Respiratory Infection in Urgent Care,” Clin. Infect. Dis., vol. 76, no. 11, pp. 1942-1948, 2023, doi: 10.1093/cid/ciad038.

DOI: https://doi.org/10.34238/tnu-jst.10742

Refbacks

There are currently no refbacks.



Remember me