FACTORS ASSOCIATED WITH FAILURE OF ANTIRECTRITIAL TREATMENT IN CHILDREN WITH HIV/AIDS AT THAI NGUYEN A HOSPITAL

Lưu Thị Thu Hà; Hoàng Thị Huế

doi:10.34238/tnu-jst.11030

FACTORS ASSOCIATED WITH FAILURE OF ANTIRECTRITIAL TREATMENT IN CHILDREN WITH HIV/AIDS AT THAI NGUYEN A HOSPITAL

About this article

Received: 29/08/24 Revised: 17/12/24 Published: 18/12/24

Authors

1. Luu Thi Thu Ha , TNU - University of Medicine and Pharmacy
2. Hoang Thi Hue, TNU - University of Medicine and Pharmacy

Abstract

ARV drugs have been shown to have a positive impact on the health of HIV-infected children. At the pediatric HIV/AIDS outpatient clinic at Thai Nguyen A Hospital, we conducted a descriptive study with a longitudinal follow-up design on 76 HIV/AIDS-infected children from 2013 to 2023, to analyze a number of factors related to antiretroviral treatment failure in HIV/AIDS-infected children. The results of our study are as follows: Factors affecting treatment failure are the time from diagnosis to late ARV use of 12 months or more, severe immunodeficiency at the start of treatment, non-adherence to treatment, and parental mortality with OR of 3.5; 4.6 and 6.3, respectively. These results highlight the need for early treatment management, maintenance and adherence to antiretroviral use, which play an important role in reducing the rate of treatment failure in HIV/AIDS-infected children.

Keywords

HIV; Children; ARV drugs; Related factors; Hospital A

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DOI: https://doi.org/10.34238/tnu-jst.11030

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