POTENTIAL APPLICATION OF NATURAL COMPOUNDS FROM MICROALGAE Euglena gracilis IN SKIN REGENERATION

Thái Hiếu Nghĩa; Nguyễn Cơ Minh; Trương Minh Khải

doi:10.34238/tnu-jst.13481

POTENTIAL APPLICATION OF NATURAL COMPOUNDS FROM MICROALGAE Euglena gracilis IN SKIN REGENERATION

About this article

Received: 25/08/25 Revised: 02/12/25 Published: 03/12/25

Authors

1. Thai Hieu Nghia, Far Eastern Federal University
2. Nguyen Co Minh, Le Hong Phong High School for the Gifted
3. Truong Minh Khai , Ho Chi Minh city University of Education

Abstract

This article reviews and evaluates the scientific evidence on the potential application of natural compounds extracted from the microalga Euglena gracilis in skin regeneration and wound healing, with the objective of establishing a scientific foundation for their consideration as alternatives to conventional dermatological treatments. A systematic literature review was conducted, in which data from published studies were collected, analyzed, and synthesized. The review emphasizes the identification of bioactive compounds, their mechanisms of action at the cellular and tissue levels, and experimental evidence of their efficacy. The findings indicate that E. gracilis is a rich source of diverse and valuable compounds, including β-1,3-D-glucan, extracellular vesicles (EVs), monohexosylceramide, fatty acids (DHA, EPA), carotenoids, and vitamins (E, C) all of which demonstrate beneficial effects on the skin. Accordingly, Euglena gracilis represents a promising vegan source for the development of advanced dermatological therapies, aligning with the increasing demand for natural, safe, and sustainable ingredients.

Keywords

Euglena gracilis; Natural compounds; Skin regeneration; Extracellular vesicles; Microalgae

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DOI: https://doi.org/10.34238/tnu-jst.13481

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