EVALUATION THE EFFECT OF STAHLIANTHUS THORELII GAGNEP. TABLES ON SOME MODELS OF BLOOD CLOTTING DISORDERS

Trần Ngọc Anh; Nguyễn Văn Dũng; Nguyễn Thị Kim Ngân; Trần Ngọc Bảo Uyên; Phó Thị Hải; Nguyễn Khánh Ly; Bùi Thị Luyến

EVALUATION THE EFFECT OF STAHLIANTHUS THORELII GAGNEP. TABLES ON SOME MODELS OF BLOOD CLOTTING DISORDERS

About this article

Received: 15/03/21 Revised: 28/04/21 Published: 29/04/21

Authors

1. Tran Ngoc Anh , TNU – University of Medicine and Pharmacy
2. Nguyen Van Dung, TNU – University of Medicine and Pharmacy
3. Nguyen Thi Kim Ngan, TNU – University of Medicine and Pharmacy
4. Tran Ngoc Bao Uyen, TNU – University of Medicine and Pharmacy
5. Pho Thi Hai, TNU – University of Medicine and Pharmacy
6. Nguyen Khanh Ly, TNU – University of Medicine and Pharmacy
7. Bui Thi Luyen, TNU – University of Medicine and Pharmacy

Abstract

This study aims to evaluate the hemostatic effect of Stahlianthus Thorelii Gagnep tables on some blood clotting disorders models. Method of experimental study on mices with models of blood clotting disorders with aspirin and heparin. The test sample was a Stahlianthus Thorelii Gagnep. tables, evaluated with two doses of 2.4 g/kg and 4.8 g/kg of mice weight. The results showed that at both dose levels of Stahlianthus Thorelii Gagnep tables on aspirin and heparin models of blood clotting disorders significantly reduces bleeding time (p < 0.5) but didn’t affect clotting time, platelet count, prothrombin time (PT) and activated partial thromboplastin time (aPTT).

Keywords

Stahlianthus Thorelii Gagnep. Tables; Hemostatic; Blood clotting disorders; Aspirin; Heparin

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