THE CLINICAL AND SUBCLINICAL CHARACTERISTICS OF CHIDREN'S THALASSEMIA TREATED CAO BANG GENERAL HOSPITAL 2021

Abstract

In this study, we analyzed the clinical and hematological characteristics of children diagnosed with thalassemia at Cao Bang General Hospital 2021. A crosssectional study were performed on 93 patients with thalassemia treated at the Cao Bang General Hospital from 6/2021 to 6/2022 by face-to-face interview and medical examination of patients. 43% of age groups with a diagnosis of thalassemia were 6-10 years old, and the average age on admission was 7.17±3.48 years old. 60.2% were Tay's ethnic, and 97.5% were diagnosed with β-thalassemia. Common clinical features were enlarged spleen (88.2%), pale mucous membranes (78.5%), paleness of the skin palm (77.4%), stunting malnutrition (51.6%), jaundice and the whites of the eyes (50.5%). Subclinical characteristics were 68.8% hypochromia red blood cells <60g/l, 95.7% Hematocrit decreased < 25%, 64.5% indirect hyperbilirubinemia, 63.4% Elevated serum iron >27 µmol/l, 69.9% Elevated serum ferritin >1000 ng/m, 55.2% skull x-ray abnormalities. The most common genotype was β-thalassemia. Common clinical features were splenomegaly, pale mucous membranes, pale palms, stunting malnutrition. Common subclinical features were moderate anemia, indirect hyperbilirubinemia, Elevated serum iron and ferritin.