DEVELOPMENT OF ANTIBACTERIAL HYDROGEL MEMBRANES FROM PVA AND CHITOSAN INCORPORATED WITH ETHANOL EXTRACT OF CATUNAREGAM SPINOSA LEAVES

Tạ Ngọc Ly; Ngô Quyết Nghị

doi:10.34238/tnu-jst.13166

DEVELOPMENT OF ANTIBACTERIAL HYDROGEL MEMBRANES FROM PVA AND CHITOSAN INCORPORATED WITH ETHANOL EXTRACT OF CATUNAREGAM SPINOSA LEAVES

About this article

Received: 02/07/25 Revised: 21/11/25 Published: 25/11/25

Authors

1. Ta Ngoc Ly , University of Science and Technology - The University of Da Nang
2. Ngo Quyet Nghi, University of Science and Technology - The University of Da Nang

Abstract

The Catunaregam spinosa plant is a potential medicinal resource with numerous valuable biological properties; however, research on this species remains limited. This study aims to fabricate hydrogel films from polyvinyl alcohol (PVA), chitosan, and ethanol extract of Catunaregam spinosa leaves, while also evaluating the antibacterial activity of the fabricated hydrogel films. The results show that the ethanol leaf extract has strong antibacterial activity against S. aureus and MRSA. The antioxidant activity of the extract was determined with an IC50 value of 22.85 µg/mL. The hydrogel film contained 5% PVA and 2% chitosan, and leaf extract reduced bacterial growth by over 99.24 % and demonstrated excellent moisture absorption capacity (5.37%). The study confirms the potential application of Catunaregam spinosa in developing skincare products, particularly for acne treatment and wound dressing, opening prospects for applications in medicine and healthcare from natural sources.

Keywords

Catunaregam spinosa; Antibacterial; Antioxidant; Chitosan; Hydrogel film

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DOI: https://doi.org/10.34238/tnu-jst.13166

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