PHYTOCHEMICAL INSIGHTS AND ANTICANCER POTENTIAL OF BIOACTIVE COMPOUNDS FROM Peltophorum pterocarpum: A REVIEW

Thái Hiếu Nghĩa; Trần Nhật Linh; Cao Nhã Uyên; Trương Minh Khải

doi:10.34238/tnu-jst.13482

PHYTOCHEMICAL INSIGHTS AND ANTICANCER POTENTIAL OF BIOACTIVE COMPOUNDS FROM Peltophorum pterocarpum: A REVIEW

About this article

Received: 25/08/25 Revised: 02/12/25 Published: 03/12/25

Authors

1. Thai Hieu Nghia, Far Eastern Federal University
2. Tran Nhat Linh, Tran Dai Nghia High School for the Gifted
3. Cao Nha Uyen, VNU-HCM High School for the Gifted
4. Truong Minh Khai , Ho Chi Minh city University of Education

Abstract

Cancer remains a global health challenge, requiring the search for new effective and safe therapies, in which natural compounds from plants are a potential resource. This review aims to systematically synthesize and evaluate scientific evidence on the anti-cancer potential of compounds from Copperpod tree (Peltophorum pterocarpum), a native woody plant species widely distributed in Vietnam. By synthesizing and analyzing reputable scientific articles, this article clarifies the chemical composition and main molecular mechanisms of the plant in supporting cancer treatment. The results show that Copperpod tree contains many valuable compounds such as triterpenoids (betulinic acid), phenolics (bergenin), and flavonoids (quercetin), with mechanisms of action including activation of mitochondria-mediated apoptosis, cell cycle arrest, and inhibition of metastasis-related signaling pathways. The presence of a complex of compounds with diverse and potentially complementary mechanisms of action suggests that P. pterocarpum is a potential research target for the development of future cancer therapeutics.

Keywords

Peltophorum pterocarpum; Anticancer activity; Betulinic acid; Apoptosis; Phytochemistry

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DOI: https://doi.org/10.34238/tnu-jst.13482

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