DETERMINATION OF PARABENS IN COSMETIC PRODUCTS BY HIGH PERFOMANCE LIQIUD CHROMATOGRAPHY

Abstract

In order to contribute  and detection of substances not banned  in cosmetics, we have developed to determined some parabens by high-performance liquid chromatography (HPLC) in lotion, lip balm. The samples have dissolved by  methanol : water (50:50), filted and eluted by high-performance liquid chromatography, reverse phase column chromatography column (C8, 150 mm x 4.6 mm, 5 µm), methanol / water mobile phase (60:40 v / v) flow rate is 1.0 ml / min, detection wavelength is 254 nm. The analytical method has specificity, linearity, accuracy, repeatability, limit of detection, LOD and limit of quantitation, LOQ  suitability for determining parabens in cosmetics. By this method, we have successfully applied to identify parabens in 07 cosmetic samples (including 04 samples of skin lotion, 03 sample of lipstick) have been in Thai Nguyen province. There were 02 samples containing both MP and PP, 04 samples containing only MP and 01 sample containing only PP.