HEMATOLOGICAL CHARACTERISTICS OF PATIENTS WITH GRANULOMATOUS LEUKEMIA AT THAI NGUYEN NATIONAL HOSPITAL

Chu Hoàng Hưng; Nguyễn Kiều Giang; Nguyễn Thị Hiền; Nguyễn Thị Mai Hương

doi:10.34238/tnu-jst.6286

HEMATOLOGICAL CHARACTERISTICS OF PATIENTS WITH GRANULOMATOUS LEUKEMIA AT THAI NGUYEN NATIONAL HOSPITAL

About this article

Received: 22/07/22 Revised: 16/09/22 Published: 16/09/22

Authors

1. Chu Hoang Hung , TNU - University of Medicine and Pharmacy
2. Nguyen Kieu Giang, TNU - University of Medicine and Pharmacy
3. Nguyen Thi Hien, TNU - University of Medicine and Pharmacy
4. Nguyen Thi Mai Huong, Thai Nguyen Medical College

Abstract

This study aims to describe hematological characteristics of patients with granulomatous leukemia at Thai Nguyen National Hospital. Cross sectional study of 31 patients with confirmed diagnosis of granulomatous leukemia according to Decision No. 1514/QD-BYT - Guidelines for diagnosis and treatment of some cancers 2020 by the Ministry of Health and according to WHO 2010. The results showed that the median value of red blood cell count was 3.1 (IQR = 2.96 – 3.28) (T/L), hemoglobin was 92.0 (IQR = 83.0 – 103.0) (g/L) and a platelet count was 145 (IQR = 66-240) (G/L), all lower than normal. The percentage of patients with average hemoglobin decreased below 100g/L was 54.8%, the number of patients with platelet count less than 100G/L was 37.8%. The median white blood cell count was 57.3 (IQR = 29.4 – 96.8) G/L, the median neutrophil count was 48.2 (IQR = 37.2 – 70.3) G/L . No BLAST cells were present in the peripheral blood. In the bone marrow, the percentage of BLAST cells (including myeloblasts and promyelocytes) was 12%, the median neutrophil count was 34 (IQR = 30 - 40). The median erythrocyte count was 7.0 (IQR = 4.0 – 8.0). The percentage of neutrophils and erythrocytes in bone marrow decreased.

Keywords

Hematology; Chronic myeloid leukemia; BLAST cell; White blood cell; Bone marrow

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DOI: https://doi.org/10.34238/tnu-jst.6286

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