RELATIONSHIP BETWEEN CARBOHYDRATE ANTIGEN 15.3 CONCENTRATION AND PERIPHERAL BLOOD CELLS’ COMPOSITION AMONG BREAST CANCER PATIENTS AT THAI NGUYEN NATIONAL HOSPITAL

Trần Bảo Ngọc; Lê Thị Hương Lan; Nguyễn Kiều Giang; Cao Thị Minh Phương

doi:10.34238/tnu-jst.6332

RELATIONSHIP BETWEEN CARBOHYDRATE ANTIGEN 15.3 CONCENTRATION AND PERIPHERAL BLOOD CELLS’ COMPOSITION AMONG BREAST CANCER PATIENTS AT THAI NGUYEN NATIONAL HOSPITAL

About this article

Received: 05/08/22 Revised: 16/09/22 Published: 16/09/22

Authors

1. Tran Bao Ngoc , TNU – University of Medicine and Pharmacy
2. Le Thi Huong Lan, Thai Nguyen National Hospital
3. Nguyen Kieu Giang, TNU – University of Medicine and Pharmacy
4. Cao Thi Minh Phuong, Thai Nguyen National Hospital

Abstract

This study aims to describe the relationship between Carbohydrate antigen 15.3 (CA-15.3) and peripheral blood cells’ composition in newly-diagnosed breast cancer patients. The study was conducted on 80 newly-diagnosed breast cancer patients at Thai Nguyen Oncology Center from January 2020 to October 2021. The method used in this study is a cross-sectional study. The research target is the results of peripheral blood cell tests by medical software. The results obtained: 13.75% of patients had increased CA 15.3. The increase of CA 15.3 increased was remarkable in patients who suffered from increase in with increased white blood cell count, increased neutrophil count, low mean corpuscular volume, and low mean corpuscular hemoglobin (p <0.05). There was no relationship between CA 15.3 and lymphocyte, monocyte count and platelet volume (p>0.05). Our finding concludes that there is a change in the characteristics of peripheral blood cells’ composition and CA 15.3 concentration in newly diagnosed breast cancer patients.

Keywords

Blood cells; Peripheral; Breast cancer; CA 15.3; Thai Nguyen

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DOI: https://doi.org/10.34238/tnu-jst.6332

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