OPTIMIZE THE EXTRACTION PROCESS OF FLAVONOID FROM BOHENIVEA L. GAUD  IN CAO BANG PROVINCE

Trần Văn Chí; Nguyễn Sinh Huỳnh; Lưu Hồng Sơn; Nguyễn Thị Hồng Ngọc; Vũ Thị Diệp

OPTIMIZE THE EXTRACTION PROCESS OF FLAVONOID FROM BOHENIVEA L. GAUD IN CAO BANG PROVINCE

About this article

Received: 19/04/19 Revised: 25/09/19 Published: 17/10/19

Authors

1. Tran Van Chi, University of Agriculture and Forestry - TNU
2. Nguyen Sinh Huynh, Cao Bang Breesing and Feed Joint Stock Company (CABACO)
3. Luu Hong Son , University of Agriculture and Forestry - TNU
4. Nguyen Thi Hong Ngoc, University of Agriculture and Forestry - TNU
5. Vu Thi Diep, University of Agriculture and Forestry - TNU

Abstract

The purpose of this study was to investigate the one way ethanol concentrations, time, temperature and the ratio of material/solvent extraction, which affected the extraction process of flavonoids from Boehmeria nivea (L.) Gaud, resulting in 70%; 90 minutes; 80°C; 1/15 (w/v). On the basis of the factors affecting the extraction conditions, we found that the solvent concentration, extraction time and material/solvent ratio strongly influence the extraction process. Application of Box-Behnken design found the optimal condition for the extraction process of Boehmeria nivea (L.) Gaud with ethanol at concentration of 71.33%, extraction time 94 minute, material/solvent ratio 1/15.67 which created the amount of flavonoids of 36.17%. Experimental results showed high degree of compatibility with the model.

Keywords

Cao Bang province, Boehmeria nivea (L.) Gaud , extraction, flavonoids, optimize

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