PHYTOCHEMICAL INVESTIGATION AND ANTIOXIDANT ACTIVITY OF TARAXACUM OFFICINALE F. H. WIGG. ASTERACEAE

Nguyễn Việt Dũng; Phạm Thị Phương; Thái Quốc Hưng; Huỳnh Lời; Huỳnh Ngọc Thụy

doi:10.34238/tnu-jst.9089

PHYTOCHEMICAL INVESTIGATION AND ANTIOXIDANT ACTIVITY OF TARAXACUM OFFICINALE F. H. WIGG. ASTERACEAE

About this article

Received: 29/10/23 Revised: 29/11/23 Published: 05/01/24

Authors

1. Nguyen Viet Dung , Buon Ma Thuot Medical University
2. Pham Thi Phuong, Buon Ma Thuot Medical University
3. Thai Quoc Hung, Buon Ma Thuot Medical University
4. Huynh Loi, Pharmaceutical Education And Research Institute, Binh Duong University
5. Huynh Ngoc Thuy, University of Medicine and Pharmacy at Ho Chi Minh City

Abstract

Dandelion is employed as a vegetable and in functional food products such as teas, extracts, and capsules. In Vietnam, this plant's chemical composition and biological effects have no report. This study aims to isolate and elucidate the compounds and evaluate the antioxidant activity using the DPPH assay. The whole plant of dandelion was macerated with 70% EtOH and subsequent fractionation. Screening for antioxidant activity was evaluated through the DPPH assay. Four compounds were isolated from the ethyl acetate extract and their antioxidant activity was determined using the DPPH assay: luteolin-7-O-b-D-glucopyranosid (IC₅₀ = 13,63 µg/mL), acid caffeic (IC₅₀ = 3,73 µg/mL), quercetin (IC₅₀ = 3,50 µg/mL), acid gallic (IC₅₀ = 1,44 µg/mL). Among them, gallic acid was isolated for the first time from Taraxacum officinale. Additionally, caffeic acid, quercetin, and gallic acid were first isolated from this species cultivated in Vietnam. This research on the topic contributes to the addition of the database, enhances practical utility, and provides direction for further studies on this species in Vietnam.

Keywords

Taraxacum officinale; Dandelion; Chemical constituents; DPPH; Antioxidant activity

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DOI: https://doi.org/10.34238/tnu-jst.9089

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