THE CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITY  OF THE WILLOW EXTRACT FROM BAC KAN PROVINCES

Hoàng Phú Hiệp; Phạm Hồng Chuyên; Từ Quang Trung; Nguyễn Mạnh Cường; Vũ Thanh Tuyết; Vũ Trọng Lượng; Phạm Văn Khang

doi:10.34238/tnu-jst.9554

THE CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITY OF THE WILLOW EXTRACT FROM BAC KAN PROVINCES

About this article

Received: 05/01/24 Revised: 25/03/24 Published: 05/04/24

Authors

1. Hoang Phu Hiep, TNU - University of Education
2. Pham Hong Chuyen, TNU - University of Education
3. Tu Quang Trung , TNU - University of Education
4. Nguyen Manh Cuong, TNU - University of Education
5. Vu Thanh Tuyet, TNU - University of Education
6. Vu Trong Luong, TNU - University of Education
7. Pham Van Khang, TNU - University of Education

Abstract

Willow (Salix babylonica) was used as medicine by ancient civilizations for its analgesic, antipyretic, and anti-inflammatory properties. The bark and leaves of the Willow contain various organic substances, especially salicin, a chemical similar to aspirin (acetylsalicylic acid), which acts as an analgesic drug. This study aimed to analyze the chemical composition and bioactivities of Willow leaf extracts collected at Bac Kan provice. The chemical composition was determined by the GC/MS method. Besides, the antioxidant activity of the samples was investigated using the DPPH method, and the antimicrobial activity was determined using the zone inhibition test. According to the GC/MS results, there are 26 compounds in the Willow extract, with seven major components (68.57% of the total composition). The Willow leaf ethanol extract has good antibacterial activity against five tested strains, with the highest activity observed against the B. subtilis strain. Ethanol extract from Willow leaves has the ability to inhibit the growth of 3 tested fungal strains, of which the best is A. Flavus. The antioxidant activity of the Willow ethanol extract was 5.36 µg/mL.

Keywords

Bioactivities; Chemical composition; GC/MS; Leaf extract; Salix babylonica

Full Text:

PDF (Tiếng Việt)

References

[1] A. Lauron-Moreau, F. E. Pitre, G. W. Argus, M. Labrecque, and L. Brouillet, “Phylogenetic relationships of American Willows (Salix L., Salicaceae),” PLoS One, vol. 10, pp. 1-12, 2015.

[2] W. Li, L. Shi, L. Han, and J. Zhang, “Development and validation of a RP-HPLC method for simultaneous determination of salicin and eight flavonoids in leaves of Salix matsudana Koidz,” Acta Chromatogr, vol. 25, pp. 735-743, 2013.

[3] H. Singh, R. Raturi, and P. Badoni, “Isolation of Secondary Metabolites from the Roots of Salix Babylonica,” IOP Conf. Ser. Mater. Sci. Eng., vol. 225, 2017, Art. no. 12094.

[4] C. Noleto-Dias, Y. Wu, A. Bellisai, W. J. Macalpine, M. H. Beale, and J. L. Ward, “Phenylalkanoid glycosides (non-salicinoids) from wood chips of Salix triandra × dasyclados hybrid willow,” Molecules, vol. 24, 2019, Art. no. 1152.

[5] Z. A. Shah, A. Hameed, A. Ahmed, S. U. Simjee, A. Jabeen, A. Ullah, and F. Shaheen, “Cytotoxic and anti-inflammatory salicin glycosides from leaves of Salix acmophylla,” Phytochem. Lett., vol. 17, pp. 107-113, 2016.

[6] J. G. Mahdi, “Medicinal potential of willow: A chemical perspective of aspirin discovery,” J. Saudi Chem. Soc., vol. 14, pp. 317-322, 2010.

[7] B. Altınterim, A. B. Ürünler, and İ. Paşa, “Effects of Willow bark (Salix alba) and its salicylates on blood coagulant,” Karaelmas Sci. Eng. J., vol. 3, pp. 37-39, 2013.

[8] M. Sobeh, M. F. Mahmoud, S. Rezq, A. E. Alsemeh, O. M. Sabry, I. Mostafa, M. A. O. Abdelfattah, K. A. El-Allem, A. M. El-Shazly, A. Yasri, and M. Wink, “Salix tetrasperma Roxb. extract alleviates neuropathic pain in rats via modulation of the NF-κB/TNF-α/NOX/iNOS pathway,” Antioxidants (Basel, Switzerland), vol. 8, pp. 482-492, 2019.

[9] K. Hostanska, G. Jürgenliemk, G. Abel, A. Nahrstedt, and R. Saller, “Willow bark extract (BNO1455) and its fractions suppress growth and induce apoptosis in human colon and lung cancer cells,” Cancer Detect. Prev., vol. 31, pp. 129-139, 2007.

[10] R. Jiao, Y. Cai, P. He, S. Munir, X. Li, Y. Wu, J. Wang, M. Xia, P. He, G. Wang, H. Yang, S. C. Karunarathna, Y. Xie, and Y. He, “Bacillus amyloliquefaciens YN201732 Produces Lipopeptides With Promising Biocontrol Activity Against Fungal Pathogen Erysiphe cichoracearum,” Frontiers in Cellular and Infection Microbiology, vol. 11, 2021, Art. no. 598999.

[11] I. Mostafa, H. A. Abbas, M. L. Ashour, A. Yasri, A. M. El-Shazly, M. Wink, and M. Sobeh, “Polyphenols from Salix tetrasperma impair virulence and inhibit quorum sensing of Pseudomonas aeruginosa,” Molecules, vol. 25, 2020, Art. no. 1341.

[12] Y. Eftekhari, A. Rustaiyan, M. Monajjemi, and R. A. Khavarinejad, “Study of anti-retroviral effects of Salix aegyptiaca L Herbal extract on HIV-1 in vitro,” Int. J. Mol. Clin. Microbiol., vol. 4, pp. 398-405, 2014.

[13]. F. Hadacek, H. Greger, Testing of antifungal natural products: Methodologies, comparability of results and assay choice. Phytochem. Anal. 2000, 11, 137–147.

[14] J. Tabart, C. Kevers, J. Pincemail, J. O. Defraigne, and J. Dommes, “Comparative antioxidant capacities of phenolic compounds measured by various tests,” Food Chem., vol. 113, pp. 1226-1233, 2009.

[15] P. H. Hoang, H. C. Pham, Q. T. Tu, and V. K. Pham, “Assessment of bioactivity of Salix babylonica extract in Thai Nguyen provice,” TNU J. Sci. Technol., vol. 228, pp. 348-353, pp. 348–353, 2023.

[16] E. González-Alamilla, M. Rivas-Jacobo, C. Sosa-Gutiérrez, L. Delgadillo-Ruiz, B. Valladares- Carranza, C. Rosenfeld-Miranda, A. Zaragoza-Bastida, N. Rivero-Pérez, E. González-Alamilla, M. Rivas-Jacobo, C. Sosa-Gutiérrez, L. Delgadillo-Ruiz, B. Valladares-Carranza, C. Rosenfeld-Miranda, A. Zaragoza-Bastida, and N. Rivero-Pérez, “Antibacterial effect of the methanol extract of Salix babylonica against important bacteria in public Health,” Abanico Vet., vol. 10, pp. 1-11, 2020.

[17] J. Tienaho, D. Reshamwala, T. Sarjala, P. Kilpeläinen, J. Liimatainen, J. Dou, A. Viherä-Aarnio, R. Linnakoski, V. Marjomäki, and T. Jyske, “Salix spp. bark hot water extracts show antiviral, antibacterial, and antioxidant activities- the Bioactive properties of 16 clones,” Front. Bioeng. Biotechnol., vol. 9, 2021, Art. no. 797939.

[18] G. Wahab, A. Sallam, A. Elgaml, M. F. Lahloub, and M. Afif, “Antioxidant and antimicrobial activities of Salix babylonica extracts,” World J. Pharm. Sci., vol. 6, pp. 1-6, 2018.

[19] K. S. Kaye, J. J. Engemann, H. S. Fraimow, and E. Abrutyn, “Pathogens resistant to antimicrobial agents: Epidemiology, molecular mechanisms, and clinical management,” Infect. Dis. Clin. North Am., vol. 18, pp. 467-511, 2004.

[20] A. R. Ndhlala, H. M. Ghebrehiwot, B. Ncube, A. O. Aremu, J. Gruz, M. Šubrtová, K. Doležal, C. P. du Plooy, H. A. Abdelgadir, and J. Van Staden, “Antimicrobial, anthelmintic activities and characterisation of functional phenolic acids of Achyranthes aspera Linn.: A medicinal plant used for the treatment of wounds and ringworm in east Africa,” Front. Pharmacol., vol. 6, pp. 274-282, 2015.

[21] D. Bajraktari, B. Bauer, and L. Zeneli, “Antioxidant capacity of Salix alba (Fam. Salicaceae) and influence of heavy metal accumulation,” Horticulturae, vol. 8, pp. 642-650, 2022.

[22] A. A. Dissanayake, C. -R. Zhang, M. K. A. Gaber, and M. G. Nair, “Salicylic glycosides in Salix mucronata with antioxidant and antiinflammatory activities,” Nat. Prod. Commun., vol. 12, pp. 1755-1758, 2017.

[23] M. S. Alam, G. Kaur, Z. Jabbar, K. Javed, and M. Athar, “Evaluation of antioxidant activity of Salix caprea flowers,” Phyther. Res., vol. 20, pp. 479-483, 2006.

[24] G. Abdel Wahab, A. Sallam, A. Elgaml, M. Farid Lahloub, M. S. Afifi Antioxidant, and M. S. Afifi, World journal of pharmaceutical sciences antioxidant and antimicrobial activities of Salix babylonica extracts,” World Journal of Pharmaceutical Sciences., vol. 6, pp. 1-47, 2018.

DOI: https://doi.org/10.34238/tnu-jst.9554

Refbacks

There are currently no refbacks.



Remember me