IDENTIFICATION OF CHEMICAL CONSTITUENTS IN THE EXTRACT OF CRATOXYLUM PRUNIFLORUM (KURZ) KURZ USING ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY COUPLED WITH QUADRUPOLE TIME-OF-FLIGHT MASS SPECTROMETRY (UPLC-QToF-MS)

Nguyễn Phú Bình; Lưu Trần Đức Lương; Lương Văn Luyện; Ngô Tuấn Vinh

doi:10.34238/tnu-jst.11934

IDENTIFICATION OF CHEMICAL CONSTITUENTS IN THE EXTRACT OF CRATOXYLUM PRUNIFLORUM (KURZ) KURZ USING ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY COUPLED WITH QUADRUPOLE TIME-OF-FLIGHT MASS SPECTROMETRY (UPLC-QToF-MS)

About this article

Received: 21/01/25 Revised: 27/02/25 Published: 27/02/25

Authors

1. Nguyen Phu Binh, Viet Bac Highlands High School
2. Luu Tran Duc Luong, Viet Bac Highlands High School
3. Luong Van Luyen, Viet Bac Highlands High School
4. Ngo Tuan Vinh , Viet Bac Highlands High School

Abstract

This study analyzes the chemical composition of Cratoxylum pruniflorum using UPLC-QToF-MS. The analysis reveals 80 compounds belonging to various chemical groups in Cratoxylum pruniflorum, including flavonoids, phenolics, alkaloids, and terpenoids. Flavonoids such as cyanidin, quercetin, and epicatechin gallate are identified as compounds with notable biological activities, including anticancer, cardioprotective, and antioxidant effects. The Cratoxylum pruniflorum extract also contains alkaloids such as oxazepam, liriodenine, and reserpine, which exhibit antimicrobial, and anticancer properties. Additionally, ganoderic acid G, HT-2 toxin, and maytenin of the terpenoid group have been widely studied, with ganoderic acid G showing potential for cancer treatment and organ protection, while maytenin demonstrates the ability to induce apoptosis in head and neck cancer cells. Some compounds with coloring ability include Cyanidin, Quercetin, and Epicatechin Gallate, Delphinidin, Protocatechuic acid, and 1,4-Dihydroxyanthraquinone. This study highlights the potential of Cratoxylum pruniflorum for drug development and biological coloring.

Keywords

Cratoxylum pruniflorum; UPLC-QToF-MS; Antioxidant activity; Anticancer activity; Antimicrobial activity

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DOI: https://doi.org/10.34238/tnu-jst.11934

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