SOME FACTORS RELATED TO HYPERGLYCEMIA IN CANCER PATIENTS IN THAI NGUYEN NATIONAL HOSPITAL | Hoa | TNU Journal of Science and Technology

SOME FACTORS RELATED TO HYPERGLYCEMIA IN CANCER PATIENTS IN THAI NGUYEN NATIONAL HOSPITAL

About this article

Received: 26/05/20                Revised: 08/07/20                Published: 10/07/20

Authors

1. Nguyen Thi Hoa Email to author, TNU - University of Medicine and Pharmacy
2. Le Thi Huong Lan, Thai Nguyen National Hospital
3. Tran Thi Kim Phuong, TNU - University of Medicine and Pharmacy

Abstract


This study aims to analyze some factor related to hyperglycemia in cancer  patients in Thai Nguyen National Hospital. By a longitudinal study method of 266 cancer patients were treated at least 3 cycles of chemotherapy. The results show that prechemotherapy, after the 3rd cycle, the mean concentration of plasma glucose levels respectively were 4.97±0.45 mmol/L, 5.33±0.99 mmol/L, 5.44±1.12 mmol/L, with statistically significant differences. After the 3rd cycle,  the prevalence of hyperglycemia in patients with colon cancer, in patients treated with 5FU, in patients treated with FOLFOX regimen were higher than  in patients with breast cancer, in patients treated with cyclophosphamid, in patients treated with AC regimen, with respectively statistically significant differences (OR: 2.31; 95% CI: 1.39-3.87; p<0.01); (OR: 2.15; 95% CI: 1.28-3.61; p<0.01); (OR: 2.06; 95% CI: 1.21-3.48; p<0.01). Increased plasma glucose levels after chemotherapy. Plasma glucose levels changed differently by tumor types chemotherapeutic agents and regimens. After the 3rd cycle, the prediabetes, diabetes were 19.9% and 3.4%.


Keywords


Gluocse; cancer; chemotherapy; related factor; Thai Nguyen National Hospital

References


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