PRELIMINARY INVESTIGATION OF THE CHEMICAL COMPOSITION OF ESSENTIAL OIL AND IN VITRO ANTI-INFLAMMATORY PROPERTY OF VARIOUS EXTRACTS FROM LANATA LEAVES (Lantana camara L.)

Nguyễn Thị Thùy Trang; Huỳnh Anh Duy

doi:10.34238/tnu-jst.8747

PRELIMINARY INVESTIGATION OF THE CHEMICAL COMPOSITION OF ESSENTIAL OIL AND IN VITRO ANTI-INFLAMMATORY PROPERTY OF VARIOUS EXTRACTS FROM LANATA LEAVES (Lantana camara L.)

About this article

Received: 12/09/23 Revised: 17/10/23 Published: 24/10/23

Authors

1. Nguyen Thi Thuy Trang, Can Tho University
2. Huynh Anh Duy , Can Tho University

Abstract

Lanata leaves (Lantana camara L.) are used to treat many diseases according to the folk experience in many countries, with data related to anti-inflammatory properties. The goal of preliminary research is to investigate the chemical composition of essential oils and in vitro anti-inflammatory effects of 05 different extracts from this medicinal plant. The essential oil of Lantana camara leaves was obtained by the hydrodistillation apparatus and analyzed on a gas chromatography–mass spectrometry system. The in vitro anti-inflammatory effect was conducted on a bovine serum albumin denaturation inhibition model. The results showed that the average yield of essential oil was 0.67% with 1,8-cineol (16.53%) and sabinen (11.49%) being the main components, along with some other notable contituents in smaller proportions. Through screening assay, the extract of ethyl acetate (EA extract) from the leaves of Lantana camara showed the most potential in vitro anti-inflammatory properties with an IC₅₀ value of 94.71 μg/mL. These results initially provide potential data on this herbal for drug discovery and development.

Keywords

Lanata leaves; Essential oil; Anti-inflammatory; Bovine serum albumin; 1,8-cineol

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DOI: https://doi.org/10.34238/tnu-jst.8747

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