MICROSCOPIC CHARACTERISTICS, CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF Amomum muricarpum Elmer | Phú | TNU Journal of Science and Technology

MICROSCOPIC CHARACTERISTICS, CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF Amomum muricarpum Elmer

About this article

Received: 10/08/23                Revised: 28/09/23                Published: 28/09/23

Authors

1. Nguyen Dinh Quynh Phu Email to author, University of Medicine and Pharmacy - Hue University
2. Doan Quoc Tuan, University of Medicine and Pharmacy - Hue University
3. Nguyen Hoai Bao Chau, University of Medicine and Pharmacy - Hue University
4. Doan Thi ai Nghia, University of Medicine and Pharmacy - Hue University
5. Le Thi Khanh Linh, University of Medicine and Pharmacy - Hue University
6. Tran Van Nguyen, University of Medicine and Pharmacy - Hue University

Abstract


Amomum muricarpum has been recorded in the North Central region in Vietnam with therapeutic properties. Studies on this species were rarely reported. The study was aimed at determining microscopic characteristics, total polyphenol content (TPC), total flavonoid content (TFC) and antioxidant activity of A. muricarpum. The microscopic features were identified by the microscopic method. TPC and TFC were determined by ultraviolet-visible spectroscopy method. The antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The microscopic characteristics of A. muricarpum’s leaves and root have been described. TPC and TFC in the ethanol extract from the aerial parts (TPC = 641.97 ± 0.66 mg GAE/g extract and TFC = 57.87 ± 0.25 mg RE/g extract) of the A. muricarpum were found to be higher than the underground parts (TPC = 466.25 ± 0.48 mg GAE/g extract, TFC = 39.56 ± 0.05 mg RE/g extract). The ethanol extract from the aerial and underground parts of A. muricarpum showed strong DPPH radical scavenging activity with IC50 values of 5.18 ± 0.20 and 6.44 ± 0.24 μg/mL, respectively, compared with quercetin used as positive control had IC50 value of 2.12 ± 0.01 μg/mL.

Keywords


Amomum muricarpum; Microscopic characteristics; Total polyphenol; Total flavonoid; DPPH

References


[1] R. Cai, X. Yue, Y. Wang, Y. Yang, D. Sun, H. Li, and L. Chen, “Chemistry and bioactivity of plants from the genus Amomum,” Journal of Ethnopharmacology, vol. 281, 2021, Art. no. 114563.

[2] H. T. Le, B. T. Tran, and B. Q. Nguyen, “Utilization pattern of genera Alpinia and Amomum (Zingiberaceae) in north central Vietnam,” In Proceeding of the 6th National Scientific Conference on Ecology and Biological Resources, 2015, pp. 1150-1154.

[3] H. T. Ha, A. T. Le, C. T. Vu, H. T. T. Tran, and C. L. T. Tran, “Diversity of Zingiberaceae from Saola nature reserve, Thua thien-hue province,” In Proceeding of the 4th National Scientific Conference on Biological Research and Teaching in Vietnam, 2020, pp. 110-116.

[4] S. T. Ninh, A. T. Le, T. T. T. Dinh, L. D. Nguyen, and T. T. Tran, “Essential Oils from the Aerial Part and Rhizome of Amomum muricarpum Elmer and Their Antimicrobial Activity,” Letters in Applied NanoBioScience, vol. 11, no. 1, pp. 3322-3328, 2021.

[5] T. B. Dau, T. Q. Vu, and T. B. Bui, “Chemical composition and antimicrobial activity of essential oils extracted from Amomum muricarpum Elmer from North Vietnam,” Physicochemical Biology, vol. 11 no. 4, pp. 523-530, 2021.

[6] G. B. Barbosa, N. P. Peteros, and E. D. Inutan, “Antioxidant activities and phytochemical screening of Amomum muricarpum, Hornstedtia conoidea and Etlingera philippinensis,Bull. Env. Pharmacol. Life Sci., vol. 5, no. 8, pp. 22-32, 2016.

[7] P. T. T. Tran, D. H. Nguyen, A. H. T. Nguyen, G. H. Do, and D. T. Nguyen, “A New Megastigmane Glycoside and Other Constituents from Amomum muricarpum Elmer,” Rec. Nat. Prod., vol. 17, no. 1, pp. 184-188, 2023.

[8] T. A. Pham, S. H. Nguyen, H. T. Le, and D. H. Nguyen, “Anti-inflammatory properties of Amomum maximum Roxb and Amomum muricarpum Elmer in the North of Vietnam,” Vietnam Journal of Biotechnology, vol. 19, no. 2, pp. 301-307, 2021.

[9] T. V. Nguyen, Testing medicinal herbs by microscopic method. Science and Technology Publishing House, Hanoi, 2003.

[10] V. Milan and M. Bharat, “Qualitative analysis, total phenol content (TPC) and total tannin content (TTC) by using different solvent for flower of Butea monosperma (Lam.) Taub. collected from Saurashtra region,” Journal of Pharmacognosy and Phytochemistry, vol. 8, no. 3, pp. 2902-2906, 2019.

[11] H. T. T. Pham, T. B. T. Nguyen, T. N. T. Nguyen, and K. H. Vo, “Total phenolic, total flavonoid contents and antioxidant potential of Common Bean (Phaseolus vulgaris L.) in Vietnam,” AIMS Agriculture and Food, vol. 5, no. 4, pp. 635-648, 2020.

[12] O. T. Asekun, S. O. Okoh, O. B. Familoni, and A. J. Afolayan, “Chemical profiles and antioxidant
activity of essential oils extracted from the leaf and stem of Parkia biglobosa (Jacq) Benth,” Research
Journal of Medicinal plant
, vol. 7, no. 2, pp. 82-91, 2013.

[13] T. M. Le, “Study on botanical characteristics and chemical composition of Amomum longiligulare T.L Wu of the Ginger family (Zingiberaceae) grown in Thach That district, Ha Noi,” Pharmacist graduation Thesis, Hanoi University of Pharmacy, 2014.

[14] N. U. Emon, S. Md. K. Hasan, Md. T. I. Taki, Md. S. U. Sawon, and Md. M. Alam, “Evaluations of Antioxidant and Anxiogenic Like Activities of Amomum aromaticum Roxb. Leaves,” European Modern Studies Journal, vol. 4, no. 1, pp. 147-155, 2020.

[15] M. Mahfur, K. Khasanah, M. A. Anindhita, S. G. Chandra, and A. N. Hidayah, “Comparison of the total phenolic and flavonoid contents of Amomum compactum Sol. Ex Maton from districts Linggo Asri and Paninggaran, Pekalongan Regency,” Sasambo Journal of Pharmacy, vol. 4, no. 1, pp. 8-13, 2023.

[16] A. A. Belew, “Total phenol contents, total favonoid contents, antioxidant activities of Methanol extracts of Amomum subulatum, Lippia adoensis, Coriandram sartivum, and Ruta chalepensis sold from Jigjiga market, Ethiopia,” Research Square, p. 18, 2023.

[17] K. D. Prakash, K. Brajesh, H. Arshad, V. Shikhar, and M. Mala, “Evaluation of antioxidant activity of large cardamom (leaves of Amomum subulatum),” Int. J. Drug Dev. & Res., vol. 4, no. 1, pp. 175-179, 2012.

[18] J. -H. Wang, J. -W. Shin, and C. -G. Son, “Antioxidant and Hepatoprotective Effects of Amomum xanthoides,The Journal of Korean Oriental Medicine, vol. 31, no. 3, pp. 98-106, 2010.

[19] H. Cory, S. Passarelli, J. Szeto, M. Tamez, and J Mattei, “The Role of Polyphenols in Human Health and Food Systems: A Mini-Review,” Front. Nutr., vol. 5, 2018, Art. no. 87.

[20] L. Xie, D. Yu, Y. Li, H. Ju, J. Chen, L. Hu, and L. Yu, “Characterization, Hypoglycemic Activity, and Antioxidant Activity of Methanol Extracts from Amomum tsao-ko: in vitro and in vivo Studies,” Front. Nutr., vol. 9, 2022, Art. no. 869749.

[21] P. Ph. Myint, K. Thu, K. C. Win, N. N. Win, and D. H. Ngwe, “A Study of Antidiabetic and Antioxidant Activities of Amomum xanthioides Wall. (Chinbaung Hpalar) Seed,” Universities Research Journal, vol. 5, no. 4, pp. 19-31, 2012.




DOI: https://doi.org/10.34238/tnu-jst.8522

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